洪義盛 (Yih-Chern Horng) 教授

國立彰化師範大學 師資培育中心

 聯絡電話:
(886)-4-7232105 ext. 3551(Office)/3527, 3552(Lab)
 E-mail:
 專長:
生物無機化學、仿生分子模擬合成研究


 簡歷:
洪義盛教授於1994年在國立彰化師範大學(NCUE)獲得化學學士學位,並在學期間跟隨廖文峰教授進行專題研究。2003年,他於美國內布拉斯加大學林肯分校(University of Nebraska-Lincoln)獲得生物化學博士學位,師從Stephen W. Ragsdale教授。2003年至2005年間,他在美國猶他大學鹽湖城分校(University of Utah-SLC)擔任Dennis R. Winge教授的博士後研究員。自2005年起,他成為國立彰化師範大學化學系的獨立教師,帶領研究團隊專注於合成與仿生催化及分子識別相關的功能性有機和無機材料。 In English: Prof. Yih-Chern Horng received his B.S. in Chemistry from National Changhua University of Education (NCUE), Taiwan, in 1994 after conducting undergraduate research with Prof. Wen-Feng Liaw. In 2003, he earned a Ph.D. in Biochemistry from University of Nebraska-Lincoln, USA, under the supervision of Prof. Stephen W. Ragsdale. During 2003-2005, he was a postdoctoral research fellow with Prof. Dennis R. Winge at University of Utah-SLC, USA. Since 2005, he has been an independent faculty member in the Department of Chemistry at NCUE, Taiwan, where his group focuses on synthesizing functional organic and inorganic materials relevant to biomimetic catalysis and molecular recognition.
 研究興趣領域:
合成與仿生催化和分子識別相關的功能性有機和無機材料



學經歷

現職
  • 1.
    國立彰化師範大學 師資培育中心 教授
    2023/08 - 現職
  • 2.
    國立彰化師範大學 國際暨兩岸事務處兩岸事務組 組長
    2021/08 - 現職
  • 3.
    國立彰化師範大學 國際暨兩岸事務處學生交流組 組長
    2021/08 - 現職
  • 4.
    國立彰化師範大學 化學系 教授
    2013/02 - 現職
學歷
  • 美國內布拉斯加州立大學林肯校區 生化系 博士
    1998/09 - 2003/07
  • 國立彰化師範大學 化學系 學士
    1990/09 - 1994/07
經歷
  • 1.
    國立彰化師範大學 化學系 系主任
    2018/08 - 2021/08
  • 2.
    國立彰化師範大學 化學系 教授
    2013/02 - 2023/08
  • 3.
    國立彰化師範大學 化學系 副教授
    2010/02 - 2013/01
  • 4.
    國立彰化師範大學 通識教育中心自然科學組 組長
    2009/09 - 2014/02
  • 5.
    國立彰化師範大學 化學系 助理教授
    2005/08 - 2010/01
  • 6.
    美國猶他大學, 鹽湖城 醫學暨生化系 博士後研究員
    2003/08 - 2005/07

113學年度 第2學期  授課表

課程代碼 課程名稱 開課班級 上課時間/節次
25019 化學科教材教法 化三 星期二 07-08
25023 專題討論化教組(二) 化四 星期四 08-09
25021 專題研究無機分析組(二) 化三 星期五 08-09


期刊論文

1. Chang-Chih Hsieh, Chia-Wei Chen, Ming-Hsi Chiang and Yih-Chern Horng, "Cu(II)-mediated tautomerization for the pyrazole-nitrile coupling reaction," Dalton Transactions, vol. 54, no. 4, pp. 1334-1342, 2025.
2. Shih-Chun Huang, Chia-Wei Chen, Roshan Satange, Chang-Chih Hsieh, Chih-Chun Chang, Shun-Ching Wang, Chi-Li Peng, Tai-Lin Chen, Ming-Hsi Chiang, Yih-Chern Horng and Ming-Hon Hou, "Targeting DNA junction sites by bis-intercalators induces topological changes with potent antitumor effects," Nucleic Acids Research, vol. 52, no. 15, pp. 9303-9316, 2024.
3. Yu-Chiao Liu, Kai-Ti Chu, Hong-Ru Wang, Gene-Hsiang Lee, Mei-Chun Tseng, Cheng-Hsin Wang, Yih-Chern Horng and Ming-Hsi Chiang, "Chloride- and Hydrosulfide-Bound 2Fe Complexes as Models of the Oxygen-Stable State of [FeFe] Hydrogenase," Angewandte Chemie International Edition, vol. 63, no. 33, pp. e202408142, 2024.
4. Chang-Chih Hsieh, Po-Kuang Liao, Chia-Wei Chen, Ming-Hsi Chiang and Yih-Chern Horng, "The effect of anions in the synthesis and structure of pyrazolylamidino copper(II) complexes," Dalton Transactions, vol. 52, no. 14, pp. 4429-4441, 2023.
5. Chang-Chih Hsieh, Cheng-Yao Li, Ming-Hsi Chiang and Yih-Chern Horng, "Catalytic O2 activation toward oxidative N–S bond formation by a thiolato Fe(III) complex," Chemical Communications, vol. 58, no. 93, pp. 12943-12946, 2022.
6. Cyong-Ru Jhan , Roshan Satange, Shun-Ching Wang, Jing-Yi Zeng, Yih-Chern Horng, Peng Jin, Stephen Neidle and Ming-Hon Hou, "Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction," Nucleic Acids Research, vol. 49, no. 16, pp. 9526-9538, 2021.
7. Chang-Chih Hsieh, Yu-Chiao Liu, Mei-Chun Tseng, Ming-Hsi Chiang and Yih-Chern Horng, "Dioxygen activation by a dinuclear thiolate-ligated Fe(II) complex," Dalton Transactions, vol. 48, no. 2, pp. 379–386, 2019.
8. Yun-Ru Wu, Chia-Ming Chang, Chia-Chi Wang, Chang-Chih Hsieh and Yih-Chern Horng, "C=N Bond Activation and Hydration by an Iron(III) Complex with Asymmetric Sulfur Oxygenation," European Journal of Inorganic Chemistry, vol. 2017, no. 4, pp. 840-843, 2017.
9. Ya-Ting Ke, Wei-Tzu Chou, Yi-Fen Chiang, Chang-Chih Hsieh and Yih-Chern Horng, "Efficient and selective separation of aqueous sulfate through recognition and precipitation," New Journal of Chemistry, vol. 41, no. 6, pp. 2249-2254, 2017.
10. Feng-Chun Lo, Chang-Chih Hsieh, Manuel Maestre-Reyna*, Chin-Yu Chen*, Tzu-Ping Ko, Yih-Chern Horng, Yei-Chen Lai, Yun-Wei Chiang*, Chih-Mao Chou, Cheng-Hung Chiang, Wei-Ning Huang, Yi-Hung Lin, D. Scott Bohle* and Wen-Feng Liaw*, "Crystal Structure Analysis of the Repair of Iron Centers Protein YtfE and Its Interaction with NO," Chemistry- A European Journal, vol. 22, no. 28, pp. 9768-9776, 2016.
11. Yih-Chern Horng, Pin-Shen Huang, Chang-Chih Hsieh and Chih-Hong Kuo, "Selective encapsulation of volatile and reactive methyl iodide," Chemical Communications, vol. 48, no. 70, pp. 8844-8846, 2012.
12. Chang-Chih Hsieh, Hon Man Lee and Yih-Chern Horng, "N-[2-(Methylsulfanyl)phenyl]-2-sulfanylbenzamide," Acta Crystallographica Section E, vol. 68, no. 8, pp. o2400, 2012.
13. Hon Man Lee, Chang-Chih Hsieh and Yih-Chern Horng, "N,N'-Bis[(1H-imidazol-1-yl)methyl]-2,20- (disulfanediyl)dianiline," Acta Crystallographica Section E, vol. 68, no. 7, pp. o2051, 2012.
14. Zih-Syuan Wu, Jui-Ting Hsu, Chang-Chih Hsieh and Yih-Chern Horng, "Assembly and disassembly of a Zn10 high-nuclearity circular helicate," Chemical Communications, vol. 48, no. 28, pp. 3436-3438, 2012.
15. Pin-Shen Huang, Chih-Hong Kuo, Chang-Chih Hsieh and Yih-Chern Horng, "Selective capture of volatile iodine using amorphous molecular organic solids," Chemical Communications, vol. 48, no. 26, pp. 3227-3229, 2012.
16. Chien-Hong Chen, Chang-Chih Hsieh, Hon Man Lee and Yih-Chern Horng, "trans-Diacetonitriletetrakis(1H-pyrazole-κN2)nickel(II)dinitrate," Acta Crystallographica Section E, vol. 65, no. 12, pp. m1680, 2009.
17. Chang-Chih Hsieh, Chia-Jung Lee and Yih-Chern Horng, "The Effects of Counteranion on the Pyrazole-Nitrile Coupling Reaction Mediated by Ni(II) Ions," Organometallics, vol. 28, no. 17, pp. 4923-4928, 2009.
18. Chang-Chih Hsieh, Wan-Jung Chao and Yih-Chern Horng, "An unique stair-like infinite chain polymer containing dimeric N2S3 square-pyramidal iron(III) complex," Inorganic Chemistry Communications, vol. 12, no. 8, pp. 778-781, 2009.
19. Kuan-Yi Wu, Chang-Chih Hsieh and Yih-Chern Horng, "Mononuclear zinc(II) and mercury(II) complexes of Schiff bases derived from pyrrolealdehyde and cysteamine containing intramolecular NH---S hydrogen bonds," Journal of Organometallic Chemistry, vol. 694, no. 13, pp. 2085-2091, 2009.
20. Chang-Chih Hsieh, Wan-Jung Chao, Yih-Chern Horng and Hon Man Lee, "Synthesis and Characterization of Nickel(II) Complex Containing 2-(t-Butylaminomethyl)pyrrole," Journal of the Chinese Chemical Society, vol. 56, no. 2, pp. 435-442, 2009.
21. Yih-Chern Horng, Tzung-Lung Lin, Cheng-Yi Tu, Ting-Ju Sung, Chang-Chih Hsieh, Ching-Han Hu, Hon Man Lee and Ting-Shen Kuo, "Preparation of a Reversible Redox-Controlled Cage-Type Molecule Linked by Disulfide Bonds," European Journal of Organic Chemistry, vol. 2009, no. 10, pp. 1511-1514, 2009.



榮譽事項

  • 校內 - 績優導師
  • 校外 - 科技部補助大專校院獎勵特殊優秀人才
  • 財團法人白沙文教基金會學術研究獎
  • 彰化師範大學教師研究成果「精實研究獎勵」
  • 國科會特殊優秀研究人才獎勵
  • 校外 - 科技部補助大專校院獎勵特殊優秀人才
  • 校內 - 教師研究成果獎勵研究精實獎
  • 彰化師範大學教師研究成果「頂級研究獎勵」